| 2021-06-28 | Sequence Musicale | Logipresse | 1986 |
| 2019-06-01 | Serendipity | The Adventure Workshop | 19xx |
| 2023-01-31 | Sergeant Seymour Robotcop | Codemasters | 1992 |
| 2012-08-25 | Serpent Madness | CPC Revue | 1985 |
| 2022-01-05 | Serpentino | Am-mag | 1988 |
| 2020-07-28 | Serpento | CPC Revue | 1989 |
| 2014-07-12 | Serra Pelada | | 2014 |
| 2020-11-15 | SetBack (27th @ CPCRetroDev 2020) | TCore | 2020 |
| 2013-07-19 | Settlement | Satchel Software | 198x |
| 2019-06-02 | Settlement XIII | The Adventure Workshop | 19xx |
| 2022-05-04 | Seven Lost Gnomes | WoW Software | 1992 |
| 2012-08-25 | Sewer Rat | | 2009 |
| 2022-05-16 | Sexopoly | | 19xx |
| 2021-06-29 | Sexy Machine | Logipresse | 1987 |
| 2015-07-20 | Sexy Test | | |
| 2012-08-25 | Sexy Words | | 1988 |
| 2023-01-31 | Seymour Goes To Hollywood
Seymour at the Movies | Codemasters | 1991 |
| 2022-07-27 | Seymour: Take One | Codemasters | 1991 |
| 2022-09-12 | Sgrizam | Dinamic | 1986 |
| 2020-11-02 | SGT. Helmet Training Day 2020 | Mojon Twins | 2020 |
| 2019-07-03 | Shackled | Usgold | 1988 |
| 2014-10-23 | Shade Of Swords
Inquisitor | Chip / Domark / Innelec | 1987/1988 |
| 2023-12-10 | Shadow Dancer | USgold | 1991 |
| 2024-03-06 | Shadow Hunter | | 2023 |
| 2023-11-03 | Shadow Maze (CPCRetroDev 2023) | Rayon Studio | 2023 |
| 2023-04-04 | Shadow of the Beast | Gremlin Graphics | 1990 |
| 2022-10-18 | Shadow Skimmer | The Edge | 1987 |
| 2019-11-10 | Shadow Soul (18th @ CPCRetroDev 2019) | | 2019 |
| 2022-10-09 | Shadow Warriors | Ocean | 1990 |
| 2024-02-05 | Shadowfire | Beyond Software | 1986 |
| 2020-12-11 | Shanghai Karate | Players | 1988 |
| 2024-03-30 | Shanghai Warriors | Players | 1989 |
| 2022-10-18 | Shao-Lin's Road | The Edge | 1987 |
| 2014-02-19 | Shape Switcher | Entropic Order | 2011 |
| 2019-02-17 | Shard of Inovar | Mastertronic | 1987 |
| 2013-09-13 | Shareplay | Goldmark Systems | 1988 |
| 2018-09-18 | Sharewatcher II | MiP Software | 1989 |
| 2024-03-30 | Shark | Players | 1989 |
| 2018-11-26 | Sharkey's Moll | Zeppelin Games | 1991 |
| 2019-05-19 | Sharpe's Deeds | Incentive Software | 1987 |
| 2023-08-18 | Shedmaster Bounds Green | Dee-kay Systems | 1987 |
| 2019-08-23 | Sheepdog Trials
Perro Pastor | Pan Books / Personal Computer News | 1984 |
| 2023-11-03 | Sheriff Duty (CPCRetroDev 2023) | Alakran Studio | 2023 |
| 2023-11-10 | Sherlock Holmes | Monser / Type and Run | 1985 |
| 2019-05-18 | Sherlock Holmes in the Case of The Beheaded Smuggler | The Adventure Workshop | 19xx |
| 2024-04-17 | Sherlock Holmes
Das Mörderschloβ
Das Moerderschloss | Weeske Software | 1985 |
| 2018-12-17 | Sherlock Holmes: The Lamberley Mystery | | 2018/1990 |
| 2018-05-14 | Sherman M4 | Loriciel | 1990 |
| 2020-09-03 | Shielding Color | | 2019 |
| 2020-04-18 | Shift | CPC Amstrad International | 1990 |
| 2024-03-18 | Shinobi | Virgin Games | 1989 |
| 2024-03-18 | Shinobi Remastered Edition | | 2020 |
| 2019-11-10 | Shinobu (13th @ CPCRetroDev 2019) | | 2019 |
| 2023-07-09 | Ship Of Doom: Adventure C | Artic Computing | 1985 |
| 2014-10-06 | Ship Pilot
Ship | Kabila / System4 | 1988 |
| 2016-05-28 | Ship Wrecked | | 19xx |
| 2023-12-08 | Ships (Amstrad Action) | Amstrad Action | 1992 |
| 2017-05-11 | Shipwrecked | Popular Computing Weekly | 1985 |
| 2018-11-29 | Shockway Rider | FTL | 1986 |
| 2012-08-25 | Shogun (CPCinfos) | Cpcinfos | 1990 |
| 2012-08-25 | Shogun (Hebdogiciel) | Hebdogiciel | 1986 |
| 2020-07-28 | Shoot (Black System) | Black System | 1990 |
| 2020-11-21 | Shoot and Run (32th @ CPCRetroDev 2020) | | 2020 |
| 2020-11-21 | Shoot to Move (37th @ CPCRetroDev 2020) | | 2020 |
| 2023-12-02 | Shoot'em | Amstrad Computer User | 1991 |
| 2023-12-04 | Shoot-Em-Up | Amstrad Computer User | 1990 |
| 2012-08-25 | Shoot-out | Martech / Electronic Arts | 1988 |
| 2020-06-11 | Shoot-out (Schneider Magazin) | Schneider Magazin | 1988 |
| 2013-03-29 | Shootbol | Scull PD | 1990 |
| 2023-01-22 | Shooter (Mike Hesser) | | |
| 2021-06-27 | Shooting | Computronic | 1987 |
| 2021-09-08 | Shooting Gallery (Amstrad Games Book) | Beam Software / Melbourne House | 1985 |
| 2021-06-19 | Shootout | Schneider Aktiv | 1987 |
| 2023-12-04 | Shoot (Amstrad Computer User) | Amstrad Computer User | 1990 |
| 2021-09-17 | Short Circuit | Ocean | 1987 |
| 2019-07-03 | Short's Fuse | Dollarsoft / Firebird | 1984 |
| 2022-08-17 | Shoulder Dash '99 | Wizcat | 1995 |
| 2022-11-23 | Shovel Adventure (1st @ CPCRetroDev 2021) | Pat Morita Team | 2021 |
| 2020-05-18 | Showdown in Tombstone City | CPC Magazin | 1985 |
| 2012-08-25 | Shufflepuck Cafe | Microids / Broderbund | 1989 |
| 2015-07-09 | Shuni Line Rax: L'Ultime Combat | MBC | 1989 |
| 2020-08-13 | Shutdown | Video Images Software | 1988/2018 |
| 2020-09-03 | Shyntow: Le Chemin de L'Esprit | | 2003 |
| 2015-10-03 | Siège | | 1985 |
| 2018-09-15 | Side Arms | Usgold / Go! | 1987 |
| 2016-11-02 | Sidegun (29th CPCRetroDev 2016) | Radical Panda | 2016 |
| 2013-08-08 | Sideral War | Delta Software | 1989 |
| 2022-04-09 | Siemb Chronicles: Arkos the Traitor | ESP Soft | 2021 |
| 2014-04-13 | Sigma Seven
Sigma 7 | Durell | 1987 |
| 2021-10-16 | Silent Service: The Submarine Simulation
Das U-Boot | Microprose / Usgold | 1986 |
| 2018-11-27 | Silent Shadow | Topo Soft | 1988 |
| 2021-03-29 | Silk Dust | | 2020/2021/2023 |
| 2018-11-27 | Silkworm | Virgin Games | 1988 |
| 2018-04-12 | Silly Number Guessing Game | | 2017 |
| 2012-08-25 | Silva: Le Temple du Diable | Lankhor | 1992 |
| 2018-12-17 | Silverwolf - Part 1 : The Quest for the Sword | | 2018 |
| 2019-07-11 | Sim City
Simcity | Infogrames | 1990 |
| 2021-05-01 | Simon | | 19xx |
| 2022-12-04 | Simon | G.T.S. Editorial | 1987 |
| 2020-07-31 | Simon (Alistair Young) | Computing with the Amstrad | 1988 |
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