| 2018-11-24 | Run the Gauntlet
Infernal Challenge | Ocean | 1989 |
| 2015-11-01 | RunCPC (6th @ CPCRetroDev 2015) | | 2015 |
| 2023-12-18 | Rune Magik | Pipeline Software | 1992 |
| 2013-08-11 | Rune-caster | Computer Gamer | 1986 |
| 2022-10-02 | Runestone | Firebird | 1986 |
| 2013-04-22 | Runner | The Amstrad User / Amsoft | 1985 |
| 2019-11-10 | Runninja (21th @ CPCRetroDev 2019) | | 2019 |
| 2022-07-02 | Ruptus | | 2022 |
| 2022-08-17 | Rush Hour Attack (Disk 50) | Cascade Games | 1986 |
| 2019-08-23 | Russian Roulette | Pan Books / Personal Computer News | 1984 |
| 2025-07-21 | Rygar: Let's Fight !!! | Usgold | 1987 |
| 2020-11-15 | RYM: Alfred's Revenge (16th @ CPCRetroDev 2020) | Crunch Games | 2020 |
| 2024-01-28 | S*M*A*S*H*E*D | Alternative Software | 1987 |
| 2019-01-08 | S.A.T.A.R
Satar | Pandora | 1987 |
| 2022-11-02 | S.H.A.R.K | Qwerty_Develop | 2022 |
| 2013-09-13 | Sabian Island | Skyslip Computers | 1988 |
| 2014-08-29 | Sabotage | Zeppelin Games | 1988 |
| 2022-03-05 | Sabotage (Amstrad Computer User)
Terrorist Attack
Ataque Terrorista | Amstrad Computer User / Amstrad User | 1984/1985/1986 |
| 2024-09-26 | Saboteur 1 | Durell | 1986 |
| 2024-12-01 | Saboteur 2 Thealfest mod | | 2024/2025 |
| 2025-06-08 | Saboteur 2: La Revanche de l'Ange
Saboteur II: Avenging Angel | Durell | 1987 |
| 2023-08-05 | Sabre Wulf | Ultimate Play The Game | 1985 |
| 2018-08-15 | Safecracker | Phoenix Publishing Associates | 1984 |
| 2014-10-17 | Sai Combat | Mirrorsoft | 1986 |
| 2012-11-16 | Saigon Combat Unit | Players | 1989 |
| 2022-10-03 | Sailing | Activision | 1987 |
| 2024-09-04 | Saint and Greavsie
Saint & Greavsie | Grandslam | 1989 |
| 2025-07-21 | Saint Dragon
St Dragon | Storm Software | 1990 |
| 2014-10-23 | Salamander | Imagine Software | 1988 |
| 2022-10-12 | Salami | Happy Computer | 1988/1989 |
| 2015-07-07 | Sally Software | PG | 1985 |
| 2012-08-25 | Salvage | Livewire | 198x |
| 2025-03-22 | Samantha Fox Strip Poker | Martech | 1986 |
| 2022-08-17 | Samurai (Black System) | Black System | 1990 |
| 2013-03-03 | Samurai Invader | Samurai Software | 1984 |
| 2015-01-23 | Samurai Trilogy | Gremlin Graphics | 1987 |
| 2016-05-28 | Sandseeker | | 19xx |
| 2020-07-25 | Santa Claus Kidz | Amstrad Computer User | 1989 |
| 2012-10-17 | Santa's Christmas Capers
Santa's Xmas Caper | Zeppelin Games | 1990 |
| 2013-09-13 | Santa's Sleigh | Computing with the Amstrad | 1986 |
| 2024-08-31 | Santas Grotty
Haggie | Computing With The Amstrad / Amstrad Semanal | 1985 |
| 2023-08-06 | Sapiens | Loriciels | 1986 |
| 2022-11-02 | Sapphire Palace | APSU Games | 2022 |
| 2014-05-12 | Saracen | USGold / Datasoft / Intellicreations | 1987 |
| 2014-12-27 | SAS Assault Course | Atlantis Software | 1987 |
| 2023-12-09 | SAS Combat Simulator | Codemasters | 1988 |
| 2025-02-19 | SAS Embassy Assault (The Amstrad Games Book) | Pitman Publishing | 1984 |
| 2016-05-28 | Satan's Domain | | 19xx |
| 2025-03-21 | Satan
Satan I+Satan II | Dinamic | 1989 |
| 2013-05-01 | Sattelite Warrior
Satellite Warrior | Amsoft | 1985 |
| 2013-08-14 | Saucer Attack | Your Computer / Sintax | 1985 |
| 2025-07-21 | Savage | Firebird | 1988 |
| 2012-08-25 | Savage Island | Tynesoft | 198x |
| 2020-07-30 | Save Santa! | Computing With The Amstrad | 1987 |
| 2018-07-07 | Save the humor | Fremos Soldiers | 2014 |
| 2022-08-17 | Save your Sister | The Adventure Workshop | 1988 |
| 2025-02-12 | Scalextric | Virgin Games / Leisure Genius | 1987 |
| 2019-12-14 | Scapeghost | Level 9 | 1989 |
| 2014-05-18 | Scary Tales | Power House | 1988 |
| 2016-06-22 | SceptreQuest I
SceptreQuest 1 | | 2016 |
| 2021-02-02 | Schools Master Pack Plus | Arc Educational Software | 198x |
| 2025-12-15 | Scooby & Scrappy Doo
Scooby-Doo and Scrappy Doo | Hitec Software | 1991 |
| 2025-12-18 | Scooby Doo In The Castle Mystery
Scoobydoo In The Castle Mystery | Elite | 1986 |
| 2020-11-03 | Scorched Planet 9620 | | 1996/2020 |
| 2023-02-23 | Scott Adams Scoops | Usgold | 1987 |
| 2020-12-04 | Scout's Honour | Electric Storm Productions | 2020/2018/1994/ |
| 2019-03-07 | Scramble | Konami | 1981/2019 |
| 2020-07-30 | Scramble (Paul Robson) | Computing with the Amstrad | 1988 |
| 2023-04-03 | Scramble Spirits | Grandslam | 1990 |
| 2013-09-26 | Screwball | Blue Ribbon | 1986 |
| 2021-10-26 | Scuba Kidz | Silverbird | 1989 |
| 2019-08-23 | Scuba
Pesca Submarina | Pan Books / Personal Computer News | 1984 |
| 2014-12-05 | SDI Now The Odds Are Even
Stategic Defence Initiative: Now the odds are even | Activision | 1989/1988 |
| 2015-07-03 | Sea Warrior 2 | Nick The Greek | 19xx |
| 2014-10-16 | Seabase Delta | Firebird / Silverbird | 1985 |
| 2022-04-19 | Search for the Fifty Pence | Adventure PD | 19xx |
| 2024-08-12 | Search for the Lost Ark (ParserComp 2023) | | 2023 |
| 2024-09-28 | Seas of Blood | Adventure International | 1986 |
| 2018-12-09 | Seaside Sourcery | | 2018/1996 |
| 2019-08-18 | Seastalker | Infocom | 1986 |
| 2024-03-04 | Secret Cavern | CPC Amstrad International | 1987 |
| 2013-09-17 | Secret Code
Codigo Secreto | Computing With The Amstrad / Amstrad Semanal | 1985 |
| 2017-03-14 | Secret England 4e/3e : Le Secret des Alchemistes | Generation 5 | 1991 |
| 2023-12-16 | Sector 5 | Crystal X | 1992 |
| 2017-05-28 | Seesaw
See-Saw | Amsoft / Andromeda Software | 1985 |
| 2016-11-04 | SEGA Columns remake for SymbOS | SymbiosiS | 2015 |
| 2023-08-13 | Segura River | Altanerus Dog | 2023 |
| 2020-06-21 | Senso | CPC Amstrad International | 1989/1988 |
| 2021-05-02 | Senso Simulator | | 2020 |
| 2021-01-28 | Senso (Patrick Hinrichs) | | 1992 |
| 2020-05-19 | Sepp Im Hochhaus
Sepp im Paternoster | CPC Magazin / Players Dream | 1986 |
| 2018-11-27 | September | Activision | 1987 |
| 2018-10-13 | Sepulcri | Reaktor | 1986 |
| 2019-06-01 | Serendipity | The Adventure Workshop | 19xx |
| 2023-01-31 | Sergeant Seymour Robotcop | Codemasters | 1992 |
| 2020-11-15 | SetBack (27th @ CPCRetroDev 2020) | TCore | 2020 |
| 2013-07-19 | Settlement | Satchel Software | 198x |
| 2019-06-02 | Settlement XIII | The Adventure Workshop | 19xx |
| 2022-05-04 | Seven Lost Gnomes | WoW Software | 1992 |
| 2012-08-25 | Sewer Rat | | 2009 |
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