| 2014-12-05 | SDI Now The Odds Are Even
Stategic Defence Initiative: Now the odds are even | Activision | 1989/1988 |
| 2018-09-03 | Se Bem me Lembro | Amstrad Magazine (Publinfor) | 1989 |
| 2015-07-03 | Sea Warrior 2 | Nick The Greek | 19xx |
| 2014-10-16 | Seabase Delta | Firebird / Silverbird | 1985 |
| 2022-04-19 | Search for the Fifty Pence | Adventure PD | 19xx |
| 2012-12-27 | Searchy | Cpc Amstrad International / Ducksoft | 1986/1985 |
| 2019-07-02 | Seas of Blood | Adventure International | 1986 |
| 2018-12-09 | Seaside Sourcery | | 2018/1996 |
| 2019-08-18 | Seastalker | Infocom | 1986 |
| 2021-06-11 | Secret Agent | Homecomputer | 1985 |
| 2024-03-04 | Secret Cavern | CPC Amstrad International | 1987 |
| 2013-09-17 | Secret Code
Codigo Secreto | Computing With The Amstrad / Amstrad Semanal | 1985 |
| 2024-01-28 | Secret Defense | Loriciel | 1988 |
| 2017-03-14 | Secret England 4e/3e : Le Secret des Alchemistes | Generation 5 | 1991 |
| 2015-10-27 | Secret England 6e/5e : Le Secret des Alchemistes | Generation 5 | 1991 |
| 2015-07-16 | Secret of Wizard | | 19xx |
| 2021-08-02 | Secret Valley | Computronic / Compute Mit | 1985 |
| 2012-08-25 | Sectar 7 | Hebdogiciel | 198x |
| 2023-12-16 | Sector 5 | Crystal X | 1992 |
| 2017-05-28 | Seesaw
See-Saw | Amsoft / Andromeda Software | 1985 |
| 2016-11-04 | SEGA Columns remake for SymbOS | SymbiosiS | 2015 |
| 2023-08-13 | Segura River | Altanerus Dog | 2023 |
| 2014-12-07 | Senda Salvaje | Zigurat | 1990 |
| 2021-06-12 | Senso | Schneider Aktiv | 1986 |
| 2020-06-21 | Senso | CPC Amstrad International | 1989/1988 |
| 2021-05-02 | Senso Simulator | | 2020 |
| 2020-04-21 | Sensor | CPC Amstrad International | 1991 |
| 2020-05-17 | Senso (Andreas Zallmann) | CPC Magazin | 1985 |
| 2023-01-22 | Senso (Mike Hesser) | | |
| 2021-01-28 | Senso (Patrick Hinrichs) | | 1992 |
| 2022-08-11 | Senso (Schneider Aktiv) | Schneider Aktiv | 1987 |
| 2020-05-19 | Sepp Im Hochhaus
Sepp im Paternoster | CPC Magazin / Players Dream | 1986 |
| 2018-11-27 | September | Activision | 1987 |
| 2018-10-13 | Sepulcri | Reaktor | 1986 |
| 2013-01-02 | Sequence (CPC Amstrad International) | Cpc Amstrad International | 1989 |
| 2021-06-28 | Sequence Musicale | Logipresse | 1986 |
| 2019-06-01 | Serendipity | The Adventure Workshop | 19xx |
| 2023-01-31 | Sergeant Seymour Robotcop | Codemasters | 1992 |
| 2012-08-25 | Serpent Madness | CPC Revue | 1985 |
| 2022-01-05 | Serpentino | Am-mag | 1988 |
| 2020-07-28 | Serpento | CPC Revue | 1989 |
| 2014-07-12 | Serra Pelada | | 2014 |
| 2020-11-15 | SetBack (27th @ CPCRetroDev 2020) | TCore | 2020 |
| 2013-07-19 | Settlement | Satchel Software | 198x |
| 2019-06-02 | Settlement XIII | The Adventure Workshop | 19xx |
| 2022-05-04 | Seven Lost Gnomes | WoW Software | 1992 |
| 2012-08-25 | Sewer Rat | | 2009 |
| 2022-05-16 | Sexopoly | | 19xx |
| 2021-06-29 | Sexy Machine | Logipresse | 1987 |
| 2015-07-20 | Sexy Test | | |
| 2012-08-25 | Sexy Words | | 1988 |
| 2023-01-31 | Seymour Goes To Hollywood
Seymour at the Movies | Codemasters | 1991 |
| 2022-07-27 | Seymour: Take One | Codemasters | 1991 |
| 2022-09-12 | Sgrizam | Dinamic | 1986 |
| 2020-11-02 | SGT. Helmet Training Day 2020 | Mojon Twins | 2020 |
| 2019-07-03 | Shackled | Usgold | 1988 |
| 2014-10-23 | Shade Of Swords
Inquisitor | Chip / Domark / Innelec | 1987/1988 |
| 2023-12-10 | Shadow Dancer | USgold | 1991 |
| 2024-03-06 | Shadow Hunter | | 2023 |
| 2023-11-03 | Shadow Maze (CPCRetroDev 2023) | Rayon Studio | 2023 |
| 2023-04-04 | Shadow of the Beast | Gremlin Graphics | 1990 |
| 2022-10-18 | Shadow Skimmer | The Edge | 1987 |
| 2019-11-10 | Shadow Soul (18th @ CPCRetroDev 2019) | | 2019 |
| 2022-10-09 | Shadow Warriors | Ocean | 1990 |
| 2024-02-05 | Shadowfire | Beyond Software | 1986 |
| 2020-12-11 | Shanghai Karate | Players | 1988 |
| 2024-03-30 | Shanghai Warriors | Players | 1989 |
| 2022-10-18 | Shao-Lin's Road | The Edge | 1987 |
| 2014-02-19 | Shape Switcher | Entropic Order | 2011 |
| 2019-02-17 | Shard of Inovar | Mastertronic | 1987 |
| 2013-09-13 | Shareplay | Goldmark Systems | 1988 |
| 2018-09-18 | Sharewatcher II | MiP Software | 1989 |
| 2024-03-30 | Shark | Players | 1989 |
| 2018-11-26 | Sharkey's Moll | Zeppelin Games | 1991 |
| 2019-05-19 | Sharpe's Deeds | Incentive Software | 1987 |
| 2023-08-18 | Shedmaster Bounds Green | Dee-kay Systems | 1987 |
| 2019-08-23 | Sheepdog Trials
Perro Pastor | Pan Books / Personal Computer News | 1984 |
| 2023-11-03 | Sheriff Duty (CPCRetroDev 2023) | Alakran Studio | 2023 |
| 2023-11-10 | Sherlock Holmes | Monser / Type and Run | 1985 |
| 2019-05-18 | Sherlock Holmes in the Case of The Beheaded Smuggler | The Adventure Workshop | 19xx |
| 2024-04-17 | Sherlock Holmes
Das Mörderschloβ
Das Moerderschloss | Weeske Software | 1985 |
| 2018-12-17 | Sherlock Holmes: The Lamberley Mystery | | 2018/1990 |
| 2018-05-14 | Sherman M4 | Loriciel | 1990 |
| 2020-09-03 | Shielding Color | | 2019 |
| 2020-04-18 | Shift | CPC Amstrad International | 1990 |
| 2024-03-18 | Shinobi | Virgin Games | 1989 |
| 2024-03-18 | Shinobi Remastered Edition | | 2020 |
| 2019-11-10 | Shinobu (13th @ CPCRetroDev 2019) | | 2019 |
| 2023-07-09 | Ship Of Doom: Adventure C | Artic Computing | 1985 |
| 2014-10-06 | Ship Pilot
Ship | Kabila / System4 | 1988 |
| 2016-05-28 | Ship Wrecked | | 19xx |
| 2023-12-08 | Ships (Amstrad Action) | Amstrad Action | 1992 |
| 2017-05-11 | Shipwrecked | Popular Computing Weekly | 1985 |
| 2018-11-29 | Shockway Rider | FTL | 1986 |
| 2012-08-25 | Shogun (CPCinfos) | Cpcinfos | 1990 |
| 2012-08-25 | Shogun (Hebdogiciel) | Hebdogiciel | 1986 |
| 2020-07-28 | Shoot (Black System) | Black System | 1990 |
| 2020-11-21 | Shoot and Run (32th @ CPCRetroDev 2020) | | 2020 |
| 2020-11-21 | Shoot to Move (37th @ CPCRetroDev 2020) | | 2020 |
| 2023-12-02 | Shoot'em | Amstrad Computer User | 1991 |
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